Before a book is printed in thousands of copies, publishers carefully check the very first copy. If the first copy has no mistakes, then they print many more. But if the first copy has errors, they correct them first so the mistakes do not spread. Similarly, when a couple chooses IVF to have a baby, doctors can check the embryo before placing it in the womb. This test is called Preimplantation Genetic Testing (PGT).
At Arihant Hospital & IVF Center in Sikar, we offer advanced Preimplantation Genetic Testing (PGT), enabling parents to ensure their baby has the best chance of growing healthy and free from certain genetic conditions.
What is Preimplantation Genetic Testing (PGT)?
Preimplantation Genetic Testing (PGT) is a special test done on embryos created during IVF (In-Vitro Fertilization). In this test:
- A very small number of cells are taken from the embryo.
- These cells are tested in a laboratory to check the chromosomes and genes.
- Only healthy embryos are selected and transferred into the woman’s womb.
In simple words, PGT is like checking the “blueprint” of a house before building it, to make sure there are no major errors.
Why is Preimplantation Genetic Testing (PGT) Done?
- PGT is recommended for couples when:
- There is a family history of genetic disorders.
- The woman has had repeated miscarriages.
- There have been multiple failed IVF cycles.
- The woman is of advanced maternal age (above 35 years).
- The man has severe sperm abnormalities.
- Parents want to reduce the risk of passing on certain hereditary conditions.
At Arihant Hospital & IVF Center in Sikar, Preimplantation Genetic Testing (PGT) gives couples confidence before embryo transfer.
Types of Preimplantation Genetic Testing (PGT)
1. PGT-A (Preimplantation Genetic Testing for Aneuploidies)
- Checks if the embryo has the correct number of chromosomes.
- Extra or missing chromosomes can cause problems like Down Syndrome.
2. PGT-M (Preimplantation Genetic Testing for Monogenic Disorders)
- Used when parents have a risk of passing on specific genetic diseases like thalassemia, cystic fibrosis, or sickle cell anemia.
3. PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)
- Used when chromosomes are broken or arranged incorrectly.
- Helps avoid miscarriages due to abnormal embryos.
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Step-by-Step Procedure of PGT
Step 1: IVF Process
In the initial phase of the IVF process, eggs are meticulously harvested from the woman’s ovaries, while sperm is collected from the man. This is typically done through a procedure known as transvaginal ultrasound aspiration. Once collected, fertilization takes place in a specialized laboratory setting where the sperm is combined with the eggs to facilitate the creation of embryos, marking the beginning of a potential new life.
Step 2: Embryo Growth
Following fertilization, the embryos are placed in a controlled environment to grow and develop. This crucial stage lasts about 5 to 6 days, during which the embryos are monitored closely until they reach the blastocyst stage. At this point, the embryos have begun to form a fluid-filled cavity and are ready for further assessment, showcasing the early signs of cellular differentiation that will lead to the development of the placenta and fetus.
Step 3: Biopsy
Once the embryos have matured, a very small portion of cells is delicately removed from each embryo using advanced techniques such as laser-assisted biopsy. This procedure is designed to be minimally invasive, ensuring the embryo remains intact and unharmed. The extracted cells, however tiny, hold vital information for the next stage of testing.
Step 4: Genetic Testing
The extracted cells are then sent to a highly specialized laboratory for comprehensive genetic analysis. Here, skilled technicians carefully examine the chromosomes and genes to identify any genetic abnormalities or inherited disorders. This testing provides critical insights into the health of the embryos and aids in making informed decisions for the subsequent steps.
Step 5: Embryo Transfer
In the final stage, only the embryos deemed healthy and free of abnormalities are selected for transfer into the woman’s womb. This process is performed with precision and care to optimize the chances of successful implantation. Any remaining viable embryos can be frozen for future use, allowing the couple additional opportunities to conceive while preserving their journey toward parenthood. At Arihant Hospital & IVF Center, we carry out Preimplantation Genetic Testing (PGT) with utmost precision and care.
Benefits of Preimplantation Genetic Testing (PGT)
- Increases IVF success rates by transferring only healthy embryos.
- Reduces risk of miscarriage by avoiding abnormal embryos.
- Prevents hereditary diseases from being passed to the baby.
- Saves time and money by improving the chances of pregnancy earlier.
- Gives peace of mind to parents with a history of genetic conditions.
Who Should Consider PGT?
- Couples with known family genetic disorders.
- Women above 35 years trying IVF.
- Couples with repeated miscarriages.
- Parents who want to ensure a healthy embryo before pregnancy.
Cost of Preimplantation Genetic Testing (PGT) in Sikar
The cost of PGT depends on the type of test (PGT-A, PGT-M, PGT-SR), the number of embryos tested, and lab facilities. At Arihant Hospital & IVF Center, we provide affordable packages for Preimplantation Genetic Testing (PGT), so families can access world-class fertility care close to home.
Why Choose Arihant Hospital & IVF Center for PGT?
- Advanced IVF and genetic testing facilities.
- Affordable and transparent pricing.
- Personalized treatment plans for each couple.
- Compassionate support throughout the IVF journey.
Arihant IVF Hospital in Sikar is a trusted center for Preimplantation Genetic Testing (PGT), helping families reduce risks and increase their chances of a healthy pregnancy.
Frequently Asked Question
No, only a small number of cells are extracted from the embryo, while the majority of the cells remain intact. As a result, the embryo continues its development seamlessly, progressing through its growth stages as intended.
Couples facing the challenges of genetic disorders, those who have experienced multiple unsuccessful attempts at in vitro fertilization (IVF), individuals who have endured recurrent miscarriages, or partners dealing with the complexities associated with advanced maternal age.
The testing process typically spans several days, during which time the embryos may be carefully preserved through freezing until the results are ready for review. This ensures that the embryos remain viable while awaiting the crucial information necessary for the next steps in the selection process.
While it cannot provide a guarantee, it greatly enhances the likelihood of achieving a healthy and successful pregnancy.
Preimplantation Genetic Diagnosis (PGD) is a procedure used in conjunction with in vitro fertilization (IVF) to identify genetic abnormalities in embryos before implantation. PGD was the original term reflecting this specific method; the terminology has evolved. Today, the broader term Preimplantation Genetic Testing (PGT) encompasses all variations of genetic testing performed on embryos, including both PGD and other methodologies that assess a wider range of genetic conditions.
If you are planning IVF and want to reduce the risk of genetic disorders, Preimplantation Genetic Testing (PGT) at Arihant Hospital & IVF Center can help you take a safer step toward parenthood.
Book your consultation at Arihant Hospital & IVF Center in Sikar today and ensure your IVF journey begins with healthy embryos and greater confidence.